Anna's research focuses on the Ebola glycoprotein with the goal of understanding its interactions with antibodies to identify potential therapeutic targets. Using hydrogen-deuterium exchange mass spectrometry (HDX-MS), she investigates the dynamic structural changes of EBOV GP upon antibody binding. In parallel, Anna is helping to pioneer new HDX-MS methodologies to improve the efficiency of data acquisition. By integrating these techniques with bioinformatics and structural modelling, she aims to uncover novel antibody binding sites and also refine HDX-MS as a powerful tool for studying protein dynamics and interactions, paving the way for targeted therapies.
Anna is a Masters student in the Struwe Lab, where she is pursuing her integrated Masters degree in Biochemistry at the University of Oxford. Having successfully completed the undergraduate component of her degree, she is now conducting her research under the guidance of Valeria Calvaresi and Weston Struwe.
